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pennylane Hardware-agnostic quantum ML framework with automatic differentiation. Use when training quantum circuits via gradients, building hybrid quantum-classical models, or needing device portability across IBM/Google/Rigetti/IonQ. Best for variational algorithms (VQE, QAOA), quantum neural networks, and integration with PyTorch or JAX. For hardware-specific optimizations use qiskit (IBM) or cirq (Google performance optimization Optimizes application performance across frontend, backend, queries, and databases. Use when performance requirements exist, when you suspect performance regressions, when Core Web Vitals or load times need improvement, when N+1 query patterns need fixing, or when profiling reveals bottlenecks. phylogenetics Build and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and FastTree (fast NJ/ML). Visualize with ETE3 or FigTree. For evolutionary analysis, microbial genomics, viral phylodynamics, protein family analysis, and molecular clock studies. pi agent Build with and use Pi, the minimal terminal coding harness. Use for installing Pi, configuring providers/models/settings/environment variables, creating Pi skills/extensions/packages/themes/prompt templates, embedding Pi through the SDK, integrating over RPC or JSON event streams, parsing sessions, running local models through the llama.cpp router, developing custom Pi providers and TUI components pinterest posts When the user wants to create Pinterest Pins, optimize Pin descriptions, or grow Pinterest presence. Also use when the user mentions "Pinterest," "Pin," "Pinterest SEO," "Pinterest description," "Pinterest board," or "Pinterest marketing." For asset specs, use visual-content. pkpd modeling Pharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when analysing concentration-time data, deriving exposure metrics, fitting PK or PD mode planning and task breakdown Breaks work into ordered tasks. Use when you have a spec or clear requirements and need to break work into implementable tasks. Use when a task feels too large to start, when you need to estimate scope, or when parallel work is possible. pmf strategy When the user wants to validate product-market fit, measure PMF, or plan before scaling. Also use when the user mentions "PMF," "product-market fit," "product market fit," "Sean Ellis test," "very disappointed," "vitamin vs painkiller," "PMF validation," "premature scaling," or "validate before scale." For GTM after validation, use gtm-strategy. podcast marketing When the user wants to plan, create, or market a podcast. Also use when the user mentions "podcast," "podcast strategy," "podcast SEO," "show notes," "podcast distribution," "Spotify podcast," "Apple Podcasts," "podcast discoverability," "PodcastEpisode schema," or "podcast repurposing." For show notes, use article-content. polars High-performance DataFrame library for Python ETL, analytics, and pandas migration. Use for expression-based data manipulation with lazy query optimization, parallel execution, streaming out-of-core processing, Arrow interoperability, and optional GPU execution. polars bio High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap, nearest, merge, coverage, complement, subtract for BED/VCF/BAM/GFF intervals. Streaming, cloud-native, faster bioframe alternative. popup generator When the user wants to add, optimize, or audit popups or modals for lead capture or offers. Also use when the user mentions "popup," "modal," "lightbox," "overlay," "exit-intent," "popup form," "modal design," "lead popup," "popup timing," or "popup triggers." For CRO, use conversion-optimization. popups When the user wants to create or optimize popups, modals, overlays, slide-ins, or banners for conversion purposes. Also use when the user mentions "exit intent," "popup conversions," "modal optimization," "lead capture popup," "email popup," "announcement banner," "overlay," "collect emails with a popup," "exit popup," "scroll trigger," "sticky bar," or "notification bar." Use this for any overlay pptx Use this skill any time a .pptx or .potx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx or .potx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slid pptx posters Create and audit editable scientific posters in macro-free PowerPoint (.pptx) from author-approved local content and assets. Use when the requested deliverable is a PowerPoint research/conference poster and exact physical, printer, accessibility, provenance, and package-security checks are required. prd-and-technical-documentation-generator name: prd-and-technical-documentation-generator press coverage page generator When the user wants to create a press coverage page, "As Seen In" section, or media mentions aggregation. Also use when the user mentions "press coverage," "media mentions," "as seen in," "as featured in," "in the news," "press mentions," "media coverage page," or "trusted by publications." For pitching journalists and press releases, use public-relations. pricing When the user wants help with pricing decisions, packaging, or monetization strategy. Also use when the user mentions 'pricing,' 'pricing tiers,' 'freemium,' 'free trial,' 'packaging,' 'price increase,' 'value metric,' 'Van Westendorp,' 'willingness to pay,' 'monetization,' 'how much should I charge,' 'my pricing is wrong,' 'pricing page,' 'annual vs monthly,' 'per seat pricing,' 'should I offer a pricing page generator When the user wants to create, optimize, or audit pricing page content and structure. Also use when the user mentions "pricing page," "pricing table," "plans," "subscription," "pricing plans," "pricing tiers," "pricing comparison," "SaaS pricing," "enterprise pricing," "API pricing," "contact sales," "pricing in nav," "public pricing," "hide pricing," or "pricing objection handling." For pricing s pricing strategy When the user wants to plan, design, or optimize pricing strategy and structure. Also use when the user mentions "pricing strategy," "pricing model," "pricing tiers," "freemium," "value-based pricing," "anchoring," "price structure," or "monetization strategy." For pricing page, use pricing-page-generator. primekg Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological data including genes, drugs, diseases, phenotypes, and more. Principal AI Code Reviewer + Senior Software Engineer / Architect Prompt name: senior-software-engineer-software-architect-code-reviewer privacy notice eu | Draft GDPR/DSGVO-compliant privacy notices as .docx for any EU/EEA jurisdiction and audience. Use when user asks to create a privacy policy/notice, mentions "Datenschutzerklärung", "politique de confidentialité", "privacy notice", needs Art. 13/14 disclosures, AI Act transparency, cookie policy, or notices for applicants ("Bewerber-Datenschutz"), employees ("Beschäftigten-Datenschutz"), B2B part privacy page generator When the user wants to create, optimize, or structure Privacy Policy page. Also use when the user mentions "privacy policy," "privacy page," "data protection," "GDPR compliance," "privacy notice," "data privacy," "CCPA," "cookie policy," or "personal data." For legal overview page, use legal-page-generator. product hunt launch When the user wants to launch on Product Hunt, prepare a PH submission, or plan launch day (hunter, first comment, timing, upvotes). Also use when the user mentions "Product Hunt," "launch on Product Hunt," "PH launch," "Product Hunt submission," "hunter," "Product of the Day," "upvotes," or "Product Hunt first comment." For multi-platform directory listings and paste-ready copy beyond PH, use dir product launch When the user wants to plan a product launch, execute launch channels, or create a launch checklist. Also use when the user mentions "product launch," "launch strategy," "product announcement," "launch channels," or "market launch." For GTM motion and positioning, use gtm-strategy. For cold start and first users, use cold-start-strategy. For Product Hunt day-of, use product-hunt-launch. product marketing When the user wants to create or update their product marketing context document. Also use when the user mentions 'product context,' 'marketing context,' 'set up context,' 'positioning,' 'who is my target audience,' 'describe my product,' 'ICP,' 'ideal customer profile,' or wants to avoid repeating foundational information across marketing tasks. Use this at the start of any new project before usi products page generator When the user wants to create, optimize, or audit a product listing or category page. Also use when the user mentions "product page," "product listing," "shop," "e-commerce products," "product catalog," "product grid," "product cards," or "product overview." For category SEO, use category-page-generator. programmatic seo When the user wants to create SEO pages at scale using templates and data—including AI-assisted, grounded copy for per-URL differentiation (vs rigid mail-merge templates). Also use when the user mentions "programmatic SEO," "programmatic SEO pages," "template pages," "scale content," "location pages," "city pages," "comparison pages at scale," "X vs Y pages," "integration pages," "pages from data, Project Evaluation for Production Decision name: project-evaluation-for-production-decision Prompt Engineering Expert name: prompt-engineering-expert Prompt Refiner name: prompt-refiner proposition checking Use when users say "does this authority support the point", "check propositions", "fact-check this argument", "verify record support", or need cited cases, statutes, exhibits, transcripts, emails, or pleadings checked against legal or factual propositions. prospecting When the user wants to find, qualify, and build a list of prospects to reach out to — across B2B SaaS, general B2B, or local small businesses. Also use when the user mentions "prospecting," "build a prospect list," "find prospects," "find leads," "lead gen list," "find SaaS companies that," "find B2B companies," "find local businesses," "ICP-fit accounts," "who should we go after," "outbound list, protocolsio integration Read, validate, and safely export protocols.io data with current official REST/MCP contracts, or create non-executing mutation plans. The bundled client makes bounded official-host GET requests only with explicit --execute. Use only for tasks explicitly targeting protocols.io or an exact protocols.io protocol version. public relations When the user wants to plan PR, write a press release, or manage media relations. Also use when the user mentions "public relations," "PR," "press release," "media relations," "news release," "journalist," "media coverage," "product announcement," or "earned media." For on-site "As Seen In" or logos page, use press-coverage-page-generator. pufferlib Version-aware guidance for PufferLib reinforcement-learning environments, vectorization, policies, PuffeRL training, evaluation, and safe checkpoint review. Use when adapting Gymnasium/PettingZoo environments to published PufferLib 3.0.0 or working with the redesigned native 4.0 source line. pydeseq2 Differential gene expression analysis for bulk RNA-seq with PyDESeq2, including formulaic designs, Wald tests, FDR correction, LFC shrinkage, and result visualization. pydicom Use pydicom to read, inspect, write, transform, and safely preflight local DICOM datasets and pixel data. Applies to DICOM metadata, transfer syntaxes, compression plugins, frames, private elements, JSON, and bounded de-identification review. pyhealth Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep staging, ICD coding, EEG events), instantiating models (Transformer, RETAIN, GAMENet, SafeDrug, MICRON, StageNet, AdaCare, CNN/RNN/MLP), training with the pylabrobot Develop and review PyLabRobot lab-automation resources, liquid-handling plans, offline simulations, and supported-device integrations. Use for PyLabRobot protocols or API questions; keep physical execution behind an explicit operator safety gate. pymatgen Analyze, validate, convert, and transform materials structures and computed materials data with current pymatgen APIs, including local phase diagrams, symmetry sensitivity, electronic-structure I/O, and explicitly bounded Materials Project queries. pymc Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and inference. pymoo Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems. pyopenms Complete mass spectrometry analysis platform. Use for proteomics and metabolomics workflows—feature detection, peptide/protein identification, label-free and isobaric quantification, adduct/accurate-mass annotation, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. For simple spectral comparison and small-molecule library matching use matchms. pysam Python/HTSlib workflows for genomic files. Use when reading, querying, filtering, or writing SAM/BAM/CRAM, VCF/BCF, FASTA/FASTQ, or tabix data with pysam, including pileup, coverage, indexing, and CRAM references. pytdc Use Therapeutics Data Commons through the PyTDC Python package for registry discovery, approved dataset access, task-aware splits, evaluator metrics, benchmark groups, and bounded molecular-oracle workflows. pytorch lightning Deep learning framework (PyTorch Lightning / lightning package). Organize PyTorch code into LightningModules, configure Trainers for multi-GPU/TPU, implement data pipelines, callbacks, logging (W&B, TensorBoard, MLflow), distributed training (DDP, FSDP, DeepSpeed), for scalable neural network training. pyzotero Interact with Zotero reference management libraries using the pyzotero Python client. Retrieve, create, update, and delete items, collections, tags, and attachments via the Zotero Web API v3. Use this skill when working with Zotero libraries programmatically, managing bibliographic references, exporting citations, searching library contents, uploading PDF attachments, or building research automati qiskit Build, simulate, transpile, and execute quantum circuits with Qiskit and IBM Quantum Runtime. Use for Qiskit 2.x circuits and operators, V2 Sampler or Estimator primitives, target-aware transpilation, local or noisy simulation, IBM QPU execution, Runtime sessions or batches, error mitigation, and Qiskit ecosystem packages.